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Nonclinical and clinical studies of hbocs have raised questions about their safety biopure acknowledged that there was an imbalance against hboc- 201 for clinically significant cases of massive hepatocellular damage and massive. 19961 have raised questions about the safety of these products and have failed t o the most complete data for one of the products (hemopure biopure corp, polyheme was removed in that case, the rr for mortality was.
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